High blood pressure is common with overweight and increases the risk of cardiovascular disease. Weight loss is one of the most effective non-pharmacological measures.
Why Does Blood Pressure Rise?
Overweight leads to increased blood volume, insulin resistance with activation of the nervous system, and mechanical effects on the kidneys.
Effect of Weight Loss
Studies show that each kg of weight loss can lower systolic blood pressure by approximately 1 mmHg. With 10 kg weight loss, the effect can be 5-10 mmHg.
GLP-1 and Blood Pressure
Clinical studies show that GLP-1 agonists lower blood pressure by 3-5 mmHg beyond the effect of weight loss alone.